Human Sera
Immunology Consultants anti-Cat SAA Antibody (Mouse - Clone #1C12) - Monoclonal
This monoclonal antibody provides highly specific detection of feline Serum Amyloid A, a major acute‑phase biomarker used to assess inflammation and systemic disease in cats. Clone 1C12 delivers strong affinity and low background in ELISA, Western blotting, and antigen‑capture assays, enabling accurate SAA quantification in serum, plasma, and purified antigen preparations. MSAA‑20A‑1C12 is ideal for veterinary diagnostics, feline health monitoring, and research on inflammatory conditions. Its consistent performance ensures reliable detection across repeated assays.
Cayman Chemical Oxyresveratrol 100mg
A resveratrol analog; scavenges H2O2 and NO (IC50 = 45.3 μM) and DPPH (IC50 = 28.9 μM); reduces brain infarct volume and reduces cytochrome c release and caspase-3 activation in an in vivo model of stroke at 10 mg/kg; inhibits tyrosinase activity (IC50s = 1.2 and 52.7 μM in mushroom and mouse melanoma B-16 cells, respectively)
Immunology Consultants anti-Bovine SAA Antibody (Mouse - Clone #1F12) - Monoclonal
This monoclonal antibody provides sensitive, specific detection of bovine Serum Amyloid A (SAA), a key acute‑phase protein used to monitor inflammation and disease in cattle. Clone 1F12 delivers strong affinity and low background in ELISA, Western blotting, and antigen‑capture assays, enabling precise quantification of SAA in serum, plasma, and purified antigen samples. MSAA‑10A‑1F12 is ideal for herd‑health monitoring, diagnostic assay development, and research on bovine inflammatory responses. Its consistent lot‑to‑lot performance ensures reliable detection across repeated assays.
Cayman Chemical OxtrIphylIn 100mg
A choline salt form of theophylline; decreases histamine-induced contractions of isolated guinea pig trachea; increases cAMP levels in guinea pig tracheal smooth muscle cells in vitro
Cayman Chemical XnthosIn 5-monphosphate 50mg
An intermediate in purine metabolism, the product of the rate limiting step in the generation of guanosine monophosphate, which is important for DNA, RNA, and glycoprotein synthesis.
Cayman Chemical PonatInIbhydrochlorIde 100mg
An inhibitor of native (IC50 = 0.37 nM) and mutant Bcr-Abl; inhibits the tyrosine kinase inhibitor-resistant mutant Bcr-AblT315I (IC50 = 2 nM), as well as Bcr-AblQ252H, Bcr-AblY253F, Bcr-AblM351T, and Bcr-AblH396P mutants (IC50s = 0.44, 0.3, 0.3, and 0.34 nM, respectively); selective for Bcr-Abl and these mutants over the insulin receptor, IGF-1R, Aurora A kinase, and Cdk2/cyclin E but does inhibit c-Src, VEGFR2, FGFR1, and PDGFRα (IC50s = 5.4, 1.5, 2.2, and 1.1 nM, respectively); inhibits proliferation of Ba/F3 cells expressing native (IC50 = 0.5 nM) or mutant Bcr-Abl (IC50s = 0.5-36 nM); reduces tumor growth in a Ba/F3 Bcr-AblT315I mouse xenograft model at 10-30 mg/kg
Cayman Chemical 7Deaza7Iodo2deoxygunos 100mg
A nucleoside derivative; has been used as an intermediate in the synthesis of fluorescent nucleotide derivatives for incorporation into single- or double-stranded oligonucleotides
Cayman Chemical IsobutyrylLcarnItInchLR 50mg
An acylcarnitine; elevated levels are associated with isobutyryl-CoA dehydrogenase deficiency
ABclonal Technology C2 Rabbit pAb
Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
Sigma Aldrich Fine Chemicals Biosciences IgM from human serum reage10MG
There are five immunoglobulin classes in humans. Out of these immunoglobulin M (IgM) is a high molecular weight protein that has five or six subunits. IgM monomers are made of two heavy chains and two light chains connected by a disulfide bond. Human serum shows low concentration of IgM monomers. It has a high carbohydrate content of about 12%. It is the first immunoglobulin produced by neonates.IgM antibodies are present as pentamers in the serum and are produced in response to antigens.IgM from human serum is purified from normal human serum by precipitation and gel filtration techniques. The immunoglobulin is determined to be atleast 95% pure by HPLC procedures.
Cayman Chemical Prfendon 50mg
An orally bioavailable pyridone derivative with antifibrotic, anti-inflammatory, and antioxidant activities; inhibits TGF-β1-stimulated increases in collagen type I, fibronectin, and Hsp47 expression in A549 lung cancer cells in a concentration-dependent manner; inhibits fibrosis and inhibits increases in collagen content, fibrocyte pool size, and the levels of chemokines CCL2 and CCL12 at 300 mg/kg in lung in a mouse model of pulmonary fibrosis induced by bleomycin; inhibits fibrosis and increases in hepatocyte apoptosis, lobular inflammation, and hepatic expression of the fibrosis-related genes Col1a1, Timp1, Tgfb1, Pdgfb, and Fgf2 in a mouse model of NASH at 280 mg/kg; inhibits NADPH-dependent lipid peroxidation in sheep liver microsomes and scavenges hydroxyl radicals (IC50s = ~6 and ~2.5 mM, respectively)
Cayman Chemical Pregnolon CarbonItrIle 50mg
A catatoxic steroid that acts as an agonist of the rodent PXR at µM concentrations; mediates induction of hepatic CYP3A, Oatp2, and Cyp7a1, regulating both xenobiotic and bile acid homeostasis
Cayman Chemical CIsatracurIumbesylate 50mg
A competitive antagonist of nAChRs and non-depolarizing muscle relaxant; inhibits acetylcholine stimulation of human adult muscle nAChRs (IC50 = 10 nM); inhibits mouse nAChRs (IC50s = 54 and 115 nM for adult and embryonic receptors, respectively); increases apoptosis in HUVEC cells; decreases proliferation of HepG2 and HUVEC cells in vitro; reduces the magnitude of electrically-evoked twitch tensions in isolated rat extensor digitorum longus and soleus sciatic nerve-muscle preparations; blocks electrically-evoked muscle twitches in anesthetized rabbits (ED95 = 0.04 mg/kg)
Cayman Chemical PalmItoleoyl EthnolamIde 100mg
An N-acylethanolamine that is produced endogenously from palmitoleic acid
